We are seeking an industrious, independent, and ambitious postdoctoral researcher to join a multi-institutional project aimed funded by Versus Arthritis focussed on developing a novel peptide-siRNA conjugate for the treatment of osteoarthritis (OA). In this project, you will be involved in the synthesis of peptide-siRNA conjugates that are designed to bind specific receptors to enable targeted delivery of disease-modifying nucleic acid agents directly to affected joint cells.

OA is a degenerative joint disorder and a leading cause of pain and disability, affecting over 500 million people worldwide. Currently, no approved treatments exist that can halt or reverse disease progression. Existing pain relief options are often ineffective or associated with adverse side effects. Small interfering RNAs (siRNAs) have emerged as a promising new class of therapeutics with unique advantages over traditional drugs. Six siRNA-based therapies are already approved for clinical use. However, a major hurdle in applying siRNA therapeutics to OA is the efficient and targeted delivery of siRNAs to joint-resident cells.

About you

You will hold a PhD in organic chemistry, medicinal chemistry, chemical biology, or a related discipline.

You should have practical experience of peptide synthesis, linker chemistries, and the preparation of conjugates with biomolecules, especially nucleic acids.

You should also have a strong track record of carrying out academic or industrial research at the interface of chemistry and biology, ideally evidenced by publications in peer-reviewed journals.

Additional information

The post is available for 12 months and will be primarily supervised by Dr Ian Eggleston (Department of Life Sciences, University of Bath). You will also work closely with Prof Mark Lindsay at Bath, and colleagues at University of Birmingham (Professor Simon Jones) and University Nottingham (Prof Vicky Chapman and Dr Federico Dajas-Bailador).

Interviews will take place in the week commencing 11 August 2025.

For an informal discussion relating to this vacancy, please contact Dr Ian Eggleston (ie203@bath.ac.uk) and Prof. Mark Lindsay (mal37@bath.ac.uk)

What we can offer you:

We consider ourselves to be a university where difference is celebrated, respected and encouraged. We have an excellent international reputation with staff from over 60 different nations and have made a positive commitment towards gender equality and intersectionality receiving a Silver Athena SWAN award. We truly believe that diversity of experience, perspectives, and backgrounds will lead to a better environment for our employees and students, so we encourage applications from all genders, backgrounds, and communities, particularly from under-represented groups, and value the positive impact that will have on the university. We are committed to maintaining a safe and secure environment for our students, staff, and community by reinforcing our commitment.

We are very proud to be an autism friendly university and are an accredited Disability Confident Leader; committed to building disability confidence and supporting disabled staff.

• Free counselling services through Health Assured
• Cycle to work scheme
• Electric vehicle salary sacrifice scheme
• Staff discount at Team Bath gym
• Staff discounts on postgraduate tuition fees
• Staff discount on language courses
• Generous employer contributory pension schemes
• Generous annual leave allowance with an additional 5 discretionary days so that you can enjoy a positive work life balance
• A wide range of personal and professional development opportunities including Apprenticeships, LinkedIn Learning and more
• Free entry to the Holburne Museum in Bath
• Local discounts and more
• A family-friendly workplace 
• An excellent reward package that recognises the talents of our diverse workforce
• Relocation allowance
• Visa reimbursement and Interest-Free Loan to help with the cost of some immigration expenses

We are committed to continually expanding our benefits to better support you and enhance your experience with us. Find out more about our benefits.

Find out from our staff what makes the University of Bath a great place to work. Follow us and on X for more information.

Closing Date: 27 Jul 2025

Department: Education & 69色情片

Salary: £38,249 to £45,413

In the role you will

• Organisation, planning, logistics and operation of our undergraduate Medicinal Chemistry teaching laboratories.
• Support our academic teaching team who lead undergraduate laboratory classes.
• Predominantly support our Medicinal Chemistry laboratories while providing support and cover for other teaching laboratories.
• Work more widely supporting the technical team, Technical Supervisors and Technical Manager who are responsible for teaching, research , operational and Health and Safety support.
• Ensure that practical classes are prepared for in advance, run in an efficient manner and that health and safety compliance is a priority.
• Ensure that the correct kit and consumables are ready, prepared/available for practical classes.
• Problem-solve where instrumentation and kit are concerned.
• Assist with practical development and problem solving where necessary.
• Communicate effectively where planning, preparation and running of classes is concerned.
• In addition to core teaching duties, support research and operational services around the Department, and where necessary, the wider Faculty.

About you

You will likely have a degree in a relevant science (e.g. Biochemistry or Chemistry) for supporting students and be highly organised. If you have experience in supporting or delivering teaching or training, or of demonstrating experiments in a higher education setting this would be ideal. We’ll also be looking for:

• An ability to organise and prioritise workload to meet required deadlines.
• Effective communication skills, with the ability to engage and build relationships with a broad range of audience.
• How you demonstrate collaboration with both your close team and other colleagues.
• Experience in health and safety compliance, including writing risk assessments and COSHH, would be an advantage.

Further information

This role is offered on a full time (36.5 hours per week) permanent basis.

For informal discussions relating to this vacancy, please contact Daniel Lou-Hing delh20@bath.ac.uk, or, Lorenzo Caggiano lc287@bath.ac.uk

What we can offer you

We consider ourselves to be a university where difference is celebrated, respected and encouraged. We have an excellent international reputation with staff from over 60 different nations and have made a positive commitment towards gender equality and intersectionality receiving a Silver Athena SWAN award. We truly believe that diversity of experience, perspectives, and backgrounds will lead to a better environment for our employees and students, so we encourage applications from all genders, backgrounds, and communities, particularly from under-represented groups, and value the positive impact that will have on the university. We are committed to maintaining a safe and secure environment for our students, staff, and community by reinforcing our commitment.

We are very proud to be an autism friendly university and are an accredited Disability Confident Leader; committed to building disability confidence and supporting disabled staff.

• Free counselling services through Health Assured
• Cycle to work scheme
• Electric vehicle salary sacrifice scheme
• Staff discount at Team Bath gym
• Staff discounts on postgraduate tuition fees
• Staff discount on language courses
• Generous employer contributory pension schemes
• Generous annual leave allowance with an additional 5 discretionary days so that you can enjoy a positive work life balance
• A wide range of personal and professional development opportunities including Apprenticeships, LinkedIn Learning and more
• Free entry to the Holburne Museum in Bath
• Local discounts and more
• A family-friendly workplace 
• An excellent reward package that recognises the talents of our diverse workforce
• Relocation allowance
• Visa reimbursement and Interest-Free Loan to help with the cost of some immigration expenses

We are committed to continually expanding our benefits to better support you and enhance your experience with us. Find out more about our benefits.

Find out from our staff what makes the University of Bath a great place to work. Follow us and on X for more information.

Closing Date: 29 Jun 2025

Department: Technical & Experimental

Salary: £26,338 to £29,959

The Rheumatology 69色情片 Group (RRG) at the University of Bath and the Royal National Hospital for Rheumatic Diseases uses anonymised databases from primary and secondary care with associated biobanks focussing on rheumatic disease for numerous research projects. The group has made significant contributions to the scientific literature with meaningful clinical impact using a variety of local, national and international databases over the last 30 years. The combined data is a valuable resource for the academic development and research needs of doctoral students, clinical fellows and other early career researchers. As data management including cleaning, curating, merging and analysing data becomes ever more complex we are seeking a research associate to support our wide ranging research group.

You will join a vibrant and productive research team, within which your role will be to coordinate and facilitate the team’s access to research databases including the Clinical Practice 69色情片 Datalink (comprising anonymised medical records from primary care), the rheumatology biobanks at the Royal United Hospitals and related lab/clinical databases at the University of Bath. You will have expertise in data management and programming to supply data to the project teams for statistical analysis and contribute to publishing results in high-quality peer-reviewed academic literature. There may be the opportunity to take ownership of certain projects depending on your interest and expertise ( e.g. statistical modelling, bioinformatics, database design).

About you

• You will hold a PhD in a relevant subject area or professional experience in relevant discipline equivalent to that of a PhD - please see the person specification in the job description for more information.
• Have experience of working with large databases requiring the skills stipulated in the person specification
• Hold excellent communication skills and enjoy working within a team environment.

Additional information

This is a part time position (0.4 FTE / 14.60 hours per week), offered on a fixed term contract for 3 years.

For further information relating to this vacancy, please contact Neil McHugh ( prsnjm@bath.ac.uk), or Anita McGrogan (am399@bath.ac.uk).

What we can offer you:

We consider ourselves to be a university where difference is celebrated, respected and encouraged. We have an excellent international reputation with staff from over 60 different nations and have made a positive commitment towards gender equality and intersectionality receiving a Silver Athena SWAN award. We truly believe that diversity of experience, perspectives, and backgrounds will lead to a better environment for our employees and students, so we encourage applications from all genders, backgrounds, and communities, particularly from under-represented groups, and value the positive impact that will have on the university. We are committed to maintaining a safe and secure environment for our students, staff, and community by reinforcing our commitment.

We are very proud to be an autism friendly university and are an accredited Disability Confident Leader; committed to building disability confidence and supporting disabled staff.

• Free counselling services through Health Assured
• Cycle to work scheme
• Electric vehicle salary sacrifice scheme
• Staff discount at Team Bath gym
• Staff discounts on postgraduate tuition fees
• Staff discount on language courses
• Generous employer contributory pension schemes
• Generous annual leave allowance with an additional 5 discretionary days so that you can enjoy a positive work life balance
• A wide range of personal and professional development opportunities including Apprenticeships, LinkedIn Learning and more
• Free entry to the Holburne Museum in Bath
• Local discounts and more
• A family-friendly workplace
• An excellent reward package that recognises the talents of our diverse workforce
• Relocation allowance
• Visa reimbursement and Interest-Free Loan to help with the cost of some immigration expenses

We are committed to continually expanding our benefits to better support you and enhance your experience with us. Find out more about our benefits.

Find out from our staff what makes the University of Bath a great place to work. Follow us and on X for more information.

Closing Date: 29 Jun 2025

Department: Education & 69色情片

Salary: £37,999 to £45,163