The role is for a postdoc in bioinformatics, who will work on studying the evolution of microbial mercury methylation across prokaryotes (on a BBSRC-funded project). The analyses will typically involve phylogenetics and computational biology. The postdoc will also assist with supervision of undergraduate and MSc student research projects to a degree appropriate to their position. Key aspects include:
As a member of 69色情片 Staff at the University of Bath, you will be encouraged to take up a minimum of 10 days professional development pro rata per year.
This role is offered on a full time (36.5 hours per week) fixed term basis with an expected start date of 01/07/2026 until 30/06/2027.
For informal discussions about the role please contact XX.
We consider ourselves to be a university where difference is celebrated, respected and encouraged. We have an excellent international reputation with staff from over 60 different nations and have made a positive commitment towards gender equality and intersectionality receiving a Silver Athena SWAN award. We truly believe that diversity of experience, perspectives, and backgrounds will lead to a better environment for our employees and students and encourage applications from all genders, backgrounds, and communities, particularly from under-represented groups, and value the positive impact that will have on the university. We are committed to maintaining a safe and secure environment for our students, staff, and community by reinforcing our Safer Recruitment commitment.
We're very proud to be a signatory of the Armed Forces Covenant. an accredited Disability Confident Leader; autism friendly university, committed to building disability confidence and supporting disabled staff.
We're continually expanding our benefits package to better support you and enhance your experience with us and the below is just an example of some of the many great benefits we offer:
Find out more about our benefits and watch the video to hear from our staff about what makes the University of Bath a great place to work as well as following us and .
Closing Date: 13 Feb 2026
Department: Education & 69色情片
Salary: £38,784 to £46,049
]]>A postdoctoral 69色情片 Associate (PDRA) position is available on a full time basis for 12 months to contribute to the project: Development and Validation of a Multi-functional, Multi-purpose Quantitative Tool for Dermal Physiologically-Based Pharmacokinetic Modeling.
Background: Topical drug products applied to the skin undergo substantial metamorphosis as they are rubbed into the application site: volatile excipients like water and alcohols evaporate, and drug and excipients absorb into the skin. The resultant residual film on the skin surface has quite different composition, structure and properties compared to the starting formulation that “came out of the tube”. Predicting drug absorption during metamorphosis and from the residual phase is an unsolved challenge. This multi-institution collaborative grant funded by the US-FDA aims to expand the capabilities of an existing physiologically based pharmacokinetic (PBPK) model simulating drug skin absorption and disposition to incorporate the metamorphosis of topical products following skin application. The final aim is developing tools that predict the performance of topical medicines and support bio(in)equivalence decisions.
This opportunity falls within an ongoing collaboration with the University of Reading, the Colorado School of Mines, the company Simulations Plus, and the FDA. Bath’s contribution to this research involves primarily the generation of experimental data to guide the development of this enhanced PBPK model by formulating products and the characterization of their metamorphotic events and their kinetics. Specifically, this PDRA will contribute to the project by: (a) formulating series of drug-vehicle combinations chosen for their potential to inform about metamorphotic events and provide relevant data for modelling purposes, (b) characterizing formulations by measuring drug stability and solubility in selected vehicles (initial formulations and after metamorphosis) and performing other tests (e.g., pH, viscosity, microscopy) as needed, (c) investigating drug and excipients (as feasible/relevant) skin permeation and disposition, (d) in collaboration with other researchers, link permeation data to metamorphosis events and formulation properties; and (d) investigating the manner in which experimental data might be exploited by a PBPK model. This challenging, fast-pace work will involve extensive formulation, IVPT and solubility tests and thus, quantitative analysis by HPLC. A successful candidate will be experienced in these techniques and will independently and pro-actively develop HPLC methods and propose alternative analytical approaches and tools which may be informative for the research aims. A background on skin formulation and percutaneous permeation is required. The successful candidate will have demonstrated capacity for carrying independent research including provision of technical reports, scientific outputs and efficient data presenting and sharing with the extended grant team and funders.
As a member of 69色情片 Stall at the University of Bath, you will be encouraged to take up a minimum of 1- days professional development pro rata per year.
The appointee to the position should understand, and have first-hand experience of the techniques used; (a) for characterizing the in vitro skin permeation and disposition of chemicals, (b) for determining solubility and stability of drugs in formulations and (c) for the quantitative analysis of drugs in biological media including HPLC. A good understanding of the pharmaceutical sciences underpinning drug delivery across biological barriers and the formulation and testing of topical drug products will be advantageous.
Enquiries and applications, including a full CV, list of publications/presentations, and two letters of reference, to Prof. Begoña Delgado-Charro (b.delgado-charro@bath.ac.uk) University of Bath, Department of Life Sciences, Claverton Down, Bath, BA2 7AY, U.K.
We consider ourselves to be a university where difference is celebrated, respected and encouraged. We have an excellent international reputation with staff from over 60 different nations and have made a positive commitment towards gender equality and intersectionality receiving a Silver Athena SWAN award. We truly believe that diversity of experience, perspectives, and backgrounds will lead to a better environment for our employees and students and encourage applications from all genders, backgrounds, and communities, particularly from under-represented groups, and value the positive impact that will have on the university. We are committed to maintaining a safe and secure environment for our students, staff, and community by reinforcing our Safer Recruitment commitment.
We're very proud to be a signatory of the Armed Forces Covenant. an accredited Disability Confident Leader; autism friendly university, committed to building disability confidence and supporting disabled staff.
This role is offered on a full time (36.5 hours per week) fixed term basis with an expected start date of 01/03/2026 for an expected period of 12 months.
For an informal discussion, please contact Begona Delgado Charro at prsbd@bath.ac.uk.
We're continually expanding our benefits package to better support you and enhance your experience with us and the below is just an example of some of the many great benefits we offer:
Find out more about our benefits and watch the video to hear from our staff about what makes the University of Bath a great place to work as well as following us and .
Closing Date: 11 Feb 2026
Department: Education & 69色情片
Salary: £38,784 to £46,049
]]>Background: Topical drug products applied to skin undergo substantial metamorphosis when rubbed into the application site: volatile excipients like water and alcohols evaporate, and drug and excipients absorb into the skin. The resultant residual film on the skin surface has quite different composition, structure and properties compared to the starting formulation that “came out of the tube”. Predicting drug absorption during metamorphosis and from the residual phase is an unsolved challenge. This multi-institution collaborative grant funded by the US-FDA aims to expand the capabilities of an existing physiologically based pharmacokinetic (PBPK) model simulating drug skin absorption and disposition to incorporate the metamorphosis of topical products following skin application. The final aim is developing tools that predict the performance of topical medicines and support bio(in)equivalence decisions.
This opportunity falls within an ongoing collaboration with the University of Reading, the Colorado School of Mines, the company Simulations Plus, and the FDA. Bath’s contribution involves primarily the generation of experimental data to guide development of this enhanced PBPK model by formulating products and the characterization of their metamorphotic events and their kinetics. Specifically, this PDRA will contribute to the project by: (a) identifying a set of critical quality attributes of topical products in their starting “as in the tube” condition, and in the residual film that forms after application to the skin, (b) describing the kinetics of metamorphosis and associated events; (c) investigating formulation compositional changes during metamorphosis and how these may impact of the drug properties, including its physical state and thermodynamic activity, and skin absorption; and (d) investigating the manner in which this information might be exploited by a PBPK model. This challenging, fast-pace work will involve a range of techniques such as IVPT, confocal Raman microscopy, X-ray, FT-IR/ATR-FT-IR, viscometry, HPLC and MS tools among others. A successful candidate will be experienced in some of these techniques and will pro-actively propose and test other approaches and tools which may be informative for the research aims. Some background on skin formulation and percutaneous permeation is desirable. The successful candidate will have demonstrated capacity for carrying independent research including provision of technical reports, scientific outputs and efficient data presenting and sharing with the extended grant team and funders. You might be required to perform some experiments at the University of Reading.
As a member of 69色情片 Stall at the University of Bath, you will be encouraged to take up a minimum of 1- days professional development pro rata per year.
The appointee to the position should understand, and have first-hand experience of the techniques used for characterizing the physical state of drugs and formulations (microscopy and spectroscopic imaging methods) and for investigating compositional changes in formulations. Ideally, some understanding of the pharmaceutical sciences underpinning drug delivery across biological barriers and the formulation and testing of topical drug products will be advantageous.
Enquiries and applications, including a full CV, list of publications/presentations, and two letters of reference, to Prof. Begoña Delgado-Charro (b.delgado-charro@bath.ac.uk) University of Bath, Department of Life Sciences, Claverton Down, Bath, BA2 7AY, U.K.
We consider ourselves to be a university where difference is celebrated, respected and encouraged. We have an excellent international reputation with staff from over 60 different nations and have made a positive commitment towards gender equality and intersectionality receiving a Silver Athena SWAN award. We truly believe that diversity of experience, perspectives, and backgrounds will lead to a better environment for our employees and students and encourage applications from all genders, backgrounds, and communities, particularly from under-represented groups, and value the positive impact that will have on the university. We are committed to maintaining a safe and secure environment for our students, staff, and community by reinforcing our Safer Recruitment commitment.
We're very proud to be a signatory of the Armed Forces Covenant. an accredited Disability Confident Leader; autism friendly university, committed to building disability confidence and supporting disabled staff.
This role is offered on a part time (18.25 hours per week) fixed term basis with an expected start date of 01/03/2026 for an expected period of 6 months.
For an informal discussion, please contact Begona Delgado Charro at prsbd@bath.ac.uk.
We're continually expanding our benefits package to better support you and enhance your experience with us and the below is just an example of some of the many great benefits we offer:
Find out more about our benefits and watch the video to hear from our staff about what makes the University of Bath a great place to work as well as following us and .
Closing Date: 11 Feb 2026
Department: Education & 69色情片
Salary: £38,784 to £46,049 Pro Rata Per Annum
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